Mutations in p53 and RAS potently cooperate in oncogenic transformation, and correspondingly, these genetic alterations frequently coexist in pancreatic ductal adenocarcinoma (PDA) and other human cancers.Previously, we identified a set of genes synergistically activated by combined Light Therapy Lamps RAS and p53 mutations as frequent downstream m
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is an inherited disorder caused by a mutation in the NOTCH 3 gene, characterized by early onset of subcortical lacunar infarcts in ornament the absence of vascular risk factors and cerebral microbleeds.Homozygosity for the factor Methylenetetrahydro
MORN5 (MORN repeat containing 5) is encoded by a locus positioned on chromosome 17 in the chicken genome.The MORN motif is found in multiple copies in several proteins including junctophilins or phosphatidylinositol PRO PB7+ phosphate kinase family and the MORN proteins themselves are found across the animal and plant kingdoms.MORN5 protein has a c
Background: A 1-month-old female snow leopard cub at Padmaja Naidu Himalayan Zoological Park exhibited excessive tear production (lachrymation).Examination diagnosed primary entropion, Pedal Covers a condition in which the eyelid margin folds inward due to developmental abnormalities, thereby resulting in corneal irritation and damage.Case Descript
Because many animal species are undescribed, and because the identification of known species is often difficult, interim taxonomic nomenclature has often been used in biodiversity analysis.By assigning individuals to presumptive species, called operational taxonomic units (OTUs), these systems speed investigations into the patterning of biodiversit